Intensification of cannabis and cannabinoids popularity has led to extensive usage of the best CBD products. Consumers may use CBD as a natural treatment for pain, arthritis, and acne. However, this doesn’t justify that they have got no side effects though they’re not lethal.
Some consumers have raised queries about safety and the possibility of CBD overdose. To others, can you overdose on CBD oil? This article presents detailed answers to these questions, among others. Secure your time and take a glance!
Studies on CBD Compound
Although cannabis tillage and use began 600 years ago, it’s pharmacological properties, and compounds rely on research. Today the historical biochemistry of CBD compounds is a scholarly work based on scientific skeptics.
Tetrahydrocannabinol (THC), which caters for psychoactive effects, was the first compound to be extracted from the cannabis plant.
Cannabidiol (CBD), the second compound isolated, is used in the manufacture of CBD oil, tinctures, gummies, capsules, and creams. Despite confusing laws on CBD legality, the Food and Drug Administration (FDA) approved Epidiolex as the first-ever cannabis-embedded medication.
In 1964, Mechoulam & Gaoni isolated Delta-9- tetrahydrocannabinol (d-9-THC) as the third and main CBD active compound. Detection of d-9-THC binding sites (located in the brainstem) and cannabinoid receptors (CB1R & CB2R) are the pillars of the cannabinoid inquiry.
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CBD and the ECS
CB1Rs maintains homeostasis and also restricts excess neuronal activities. However, the purposes are not clear due to many interconnections with other neurotransmitter systems. In contrast, CB2Rs stimulate the immune system and regulate cytokine release.
CB1Rs are based in the basal ganglia, substantia nigra, cerebellum, hippocampus, limbic system, thyroid, testicular tissue, bones, liver, and peripheral nervous system. While CB2Rs are located in the immune cells, gastrointestinal system, and spleen. And relatively, in the brain and peripheral nervous system.
Amazingly, CB1Rs & CB2Rs are traceable in the human placenta, where they synchronize serotonin transporter activities.
The present scientific skeptics show four major CBD compounds: cannabinol, CBD, d-9-THC, and d-8-THC, with CBD and d-9-THC being the main compounds.
Full-Spectrum vs. Broad-Spectrum CBD
Full-spectrum and broad-spectrum CBD are terms used interchangeably but have a whole difference in their meaning. Their differences are noticeable from their literal meaning, compounds, and usage.
Full-spectrum has all cannabinoids, psychoactive compounds, and THC present for the entourage effect. In contrast, broad-spectrum CBD has all cannabinoids a cannabis plant has to offer except, THC.
The absence of THC is what differentiates broad-spectrum from full-spectrum CBD. Notably, broad-spectrum has all other cannabinoids, flavonoids, and terpenes, which offer the entourage effect.
Broad-spectrum gives the entourage effect merits to the brands’ users, with less THC psychoactive effects risk. This means that it has a real entourage effect, unlike full-spectrum, which presents psychoactive effects risk to the CBD consumer.
Unlike broad-spectrum CBD, full-spectrum CBD has other cannabinoid compounds (CBN, CBC, CBG, CBDA & CBDV), making it expensive.
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When to Use Full-Spectrum and Broad-Spectrum CBD
Full-spectrum and broad-spectrum CBD differ in their consumer preferences. Full-spectrum is best for:
- Persons recommended to specific THC to CBD ratio
- Individuals from states where cannabis is legal
- Persons with more chronic conditions that Broad-spectrum CBD cannot ease
Contrary, broad-spectrum is best for:
- THC sensitive persons
- Persons with conditions that CBD isolates alone cannot ease
- First-time users who are THC hesitant
- Consumers from states where cannabis is illegal or in tight 0.3 THC law on CBD products
In wrap-up, full-spectrum CBD involves all-natural compounds of the cannabis plant, while broad-spectrum contains only risk-free psychoactive compounds.
Can You Overdose on CBD?
Are you worried about CBD oil overdose? Don’t fret!
After scads of claims of people visiting emergency rooms after overdosing THC-rich consumables, CBD users have had worries of similar effects. Some have asked, can you overdose on CBD? Others, what’s the right amount of CBD one should take?
You must understand that overdose has distinct meanings. First, it may mean excessive dosage, which is fatal. Secondly, it may mean an accidental intake of two doses instead of one.
So, can you overdose on CBD oil? Or any other dose of CBD? Let’s know the truth!
As a non-toxic product, CBD possesses no poisonous effects. And unlike prescription drugs that have reported deaths, CBD has not recorded any human fatality. It means that there might be lower risks of CBD overdose from all cannabidiol brands.
Since cannabidiol doesn’t react in a risky way with the body, CBD may not lead to a deadly overdose. So, it is possible to take lots of CBD at once. However, you’re likely to experience adverse side effects.
Is CBD Addictive?
According to the World Health Organization (WHO), CBD portrays no addictive signs in humans. More research post that cannabidiol doesn’t have addictive substances. These shreds of evidence might prove that CBD products aren’t addictive and that they lack addictive characteristics.
Amazingly, drug addicts may use cannabidiol (CBD) is used as an organic curative to return to a healthy life. The research reported that CBD helps addicts recover by lowering their heroin cravings during rehab.
Though many consumers often use CBD products, they don’t consume them due to physical addiction, but as a dietary supplement.
In short, there aren’t proves of health-related problems or addictive claims of CBD consumption. Hence, the short answer is no, CBD is not addictive. You can consume it without being “hooked.”
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How to Dose CBD
Since personal experiences with cannabidiol use vary from person to person, you must opt for a CBD dose that suits your preferences based on the following factors:
- CBD tolerance
- Kg of body weight
You can select your ideal dosage via trial and error during the early days of use. To find the ideal dosage for you, consult with a doctor. Nevertheless, here are some steps you can take to see if your dosage works for you.
Start with a low dose
Begin with lower amounts of CBD, and work your way up gradually. With this, you rest assured of having a starting point by having your preferable dose of CBD.
Evaluate the effectiveness
Though manufacturers present a detailed report of CBD concentration in ml per packaging, you don’t need the information. But instead, the effectiveness of the product based on your needs. You can do quick calculations by considering the bottle size in ml and CBD amount on the label in mg.
Suppose the bottle indicates 50 ml capacity and 800mg CBD quantity. Divide the CBD quantity with bottle size. That is, 800mg ÷ 50ml = 16mg/ml CBD. With this, your dosage is 16mg of pure CBD.
Decide on your dose
No single dose of CBD works for everyone. Dosage differs from person to person, and so you need to choose that which suits your preferences.
For instance, opt for products high in CBD and low in THC if you’re a beginner. If you don’t need a product with THC traces, then CBD isolate will work best.
Again, to get the best dosage for you, consult with a medical physician.
CBD Overdose: FAQs
Is CBD Overdose Possible?
Yes. Because, from its meaning, an overdose may mean excessive dosage or accidental intake of two doses simultaneously. And with scenarios, an overdose on CBD is possible. However, overdose on CBD is not fatal.
What dose of CBD can be fatal?
According to the World Health Organization (WHO), CBD products are safe. This is because CBD has no health problems, and possess a reputable profile since they’re pure isolates of the cannabis plant. With this, no specific dose of CBD is fatal. However, there may be a fatal cut off point.
How to find out that a person has overdosed CBD?
Since cannabinoid receptors are not located in the brainstem, an overdose of CBD is not life-threatening. However, it leaves the user in a deteriorating state due to the side effects, though not deadly.
Symptoms of CBD overdose include diarrhea, nausea, digestive issues, and extreme mood swings.
What immediate help with an overdose of CBD?
Once you notice someone has overdosed CBD and the symptoms are severe, you can immediately help by stopping the intake of CBD and monitor for worsening symptoms. Call for clinical help or bringing the person to the nearest healthcare center.
What maximum dosages of CBD can a person take?
CBD dosage and cannabis products are subject to discussion. Hence there is no maximum dose of CBD a person can take because each person responds differently to a specific dosage.
The ideal dosage depends on body weight, individual CBD tolerance, product potency, and desired effects.
Can a pet overdose on CBD?
Similarly, to humans, pets can too overdose on CBD, resulting in unwanted signs and symptoms. If they occur, you can help mitigate the conditions and your furry friend back to normal by calling a vet immediately. CBD supplements with over 0.3 THC content, are likely to cause an overdose in pets.